In 1918, a handful of smallpox cases on campus prompted the administrators to (once again) require everyone be vaccinated.
An illustration from 1914 about the results of a couple once vaccinated.
"On Tuesday of last week, notices were posted to the effect that all persons connected with the college must either be vaccinated or leave the school by Friday, Nov. 15th. This order was issued on account of the outbreak of several smallpox cases in various parts of the campus, making it appear as though there might be a general outbreak of smallpox over the entire college. Consequently on Wednesday morning there was a rush of students to the hospital to be vaccinated."